About Chemical Biology
Email this to a friend
Email your librarian
Add to del.icio.us
Digg this story
Share on Facebook
РОССИЙСКАЯ АКАДЕМИЯ НАУК
ИНСТИТУТ ХИМИИ TBEPДОГО ТЕЛА
|Карта сайта Language
Hilderbrand's team used yttrium oxide nanoparticles for the in vivo imaging. The oxide is known to have good stability to light, unlike some imaging materials such as organic dyes. By attaching a polymer coating the team was able to make the particles water-soluble - a requirement for in vivo imaging. The researchers then incorporated a fluorophore on the coating to make the particles luminescent. They found that the particles overcame the problem of autofluorescence and could be used to generate clear images.
"Future use in angiography, intraoperative imaging or other bioimaging applications"
Manuel Perez, an expert in the field of nanoparticle technologies and molecular imaging, from the University of Central Florida, Orlando, US, says that the work is promising. 'The novelty of the approach is that the nanoparticles are composed of less toxic materials, in contrast to quantum dots,' he explains, suggesting an added benefit over current imaging methods.
The researchers suggest that the nanoparticles could find a future use in angiography, intraoperative imaging or other bioimaging applications.
Enjoy this story? Spread the word using the 'tools' menu on the left or add a comment to the Chemistry World blog.
Link to journal article
Upconverting luminescent nanomaterials: application to in vivo bioimaging
Also of interest
Fluorescent probes are shedding light on bacterial infection.
A DNA-binding Gd chelate for the detection of cell death by MRI